Effect of Antiviral Therapy for HCV Treatment in the Presence of Hepatocyte Growth Factor
نویسندگان
چکیده
The effect of antiviral therapy during Hepatitis C Virus (HCV) infection is the focus this study. HCV destroys healthy hepatocyte cells in human liver, causing cirrhosis and hepatocellular carcinoma. We introduce a cell-population model representing long-term dynamics response to drug therapies. proliferation existing can create system. Such models are based on susceptible hepatocytes, infected hepatocytes with interactive dynamics, which give complete understanding host system presence therapy. Infection-free equilibrium endemic two states absence drugs. existence stability conditions for both systems presented. also construct an optimal control find strategy. Numerical results show that effects rate critical changes model. impact different weight factors problem analysed through numerical simulation.
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ژورنال
عنوان ژورنال: Mathematics
سال: 2023
ISSN: ['2227-7390']
DOI: https://doi.org/10.3390/math11030751